Van de Ven Brace Ends The Toffees' Run at Brand New Stadium
Micky van de Ven emerged as the first backline player to score twice in a Premier League match for Tottenham since Jan Vertonghen in March 2013.
At a glance
The Spurs defender nods home two times in opening period
Everton's Jake O'Brien has goal ruled after VAR review
Pape Matar Sarr scores third in dying moments
This loss is the Merseyside club's first at Hill Dickinson Stadium
The Tottenham defender scored on two occasions as Tottenham extended their winning streak in away games in the top division and delivered Everton their first defeat at Hill Dickinson Stadium.
Everton were unbeaten in their last five matches at their new ground at the dockside location, having departed their historic home behind after more than a century at the end of last season.
But Tottenham's leader the Dutchman pounced on two occasions from set-pieces in the opening 45 minutes to put their strong form at risk, and they were unable to turn it around before Pape Matar Sarr - assisted by former Toffees attacker the Brazilian - nodded in a final goal to put the game to bed.
The Everton defender thought he had levelled the scores a short while after Van de Ven's first goal, directing a bullet header past Guglielmo Vicario from an Everton corner.
Beto, in the meantime, missed a number of opportunities, while Vicario made a succession of fine saves to ensure the London club went five away games without defeat in the Premier League.
But the video assistant referee stepped in, instructing Craig Pawson to review the score on the screen and the referee ruled that the winger and the attacker were in offside positions and had impeded with the Spurs keeper.
This victory elevates the manager's team into third place in the Premier League, a handful of points off local foes and leaders Arsenal.
Everton remain in 14th position and sit six points clear of the relegation zone.
Tottenham analysis: The defender excels in role at each end of pitch
Following a uninspiring weekday performance in the European competition against Monaco, where they managed a only two shots on target, Frank opted for Randal Kolo Muani up front instead of ex-Everton forward Richarlison.
The summer signing was unable to make much of an impact before being replaced for Richarlison after 60 minutes on the field, but it turns out he wasn't needed in the end.
Defender the Dutchman converted into an offensive threat to be feared.
Spurs' opening strike came from a well-worked corner routine, with the midfielder heading the ball back across the face of goal for an free the defender to head home.
And the captain - stepping up as skipper in Cristian Romero's absence - notched his second in added time as he rose above the England keeper to head home.
Van de Ven was just as impressive in defence, combining well with Kevin Danso as the pair handled excellently with the 34 crosses sent their way by Everton.
Toffees breakdown: Everton lacking finishing touch
The club's new home had been a fortress, but it seems the freshness may have worn off slightly and supporters headed to the gates after the midfielder's third for Spurs.
The break in the team's unbeaten home run won't be a massive worry for the manager, but their striker situation are.
Beto and the other striker - the Everton's pair of recognised strikers - had netted just one league goal combined before Sunday's match.
And they were unable to add to that miserable record on a wet and gloomy night on in Liverpool.
Beto's performance was epitomized when he opted to bicycle-kick a golden opportunity from close range, even with having room and opportunity to reposition for a simpler shot that would have tested Vicario.
The substitute, as well, was unable to make an impact after replacing Beto in the second half.
It wasn't for a lack of chance. Most of the home side's offensive moves came through Grealish and the forward, who relentlessly delivered threatening balls into the Tottenham penalty area.
Upcoming fixtures for these two sides?
Everton: The team travel to Sunderland in the top flight on Monday, 3 November at 20:00 GMT.
Spurs: Spurs go to St James' Park on Wednesday, 29 October for their fourth-round Carabao Cup tie against Newcastle.